319460-85-0
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319460-85-0

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Product Description

Name

Axitinib

Synonyms

AG-013736 N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide;AXITINIB;Axtinib;AVERMECTINB;[14C]-Axitinib;Axitinib (usan)

Molecular Formula

C22H18N4OS

Molecular Weight

386.47000

CAS Number

319460-85-0

purity

97%

Storage conditions

Sealed in dry,2-8°C










application:Axitinib (AG013736; trade name Inlyta) (CAS No.: 319460-85-0) is a small molecule tyrosine kinase inhibitor developed by Pfizer. It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models and has shown partial responses in clinical trials with renal cell carcinoma (RCC) and several other tumour types.
It was approved for RCC by the U.S. Food and Drug Administration after showing a modest increase in progression-free survival, though there have been reports of fatal adverse effects.



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